Research Article

Apoptotic Inducement of Neuronal Cells by Aluminium Chloride and the Neuroprotective Effect of Eugenol in Wistar Rats

Table 1

Effects of eugenol on proapoptotic and antiapoptotic proteins following aluminium-induced neurotoxicity in rats.

ParameterEGEG+AlCl3AlCl3CTRL

Bcl-2 (ng/mg)15.25 ± 0.219.02 ± 0.455.12 ± 0.12+17.06 ± 062
Bax (ng/mg)2.41 ± 0.8212.21 ± 0.7119.52 ± 0.60+3.21 ± 0.92
Bcl-2/Bax6.32 ± 0.010.74 ± 0.010.26 ± 0.03+5.31 ± 0.02

; ; one-way Tukey’s post hoc test: when compared with the aluminium-treated group and when the AlCl3 group is compared to the control.