Nomogram to Predict Poor Outcome after Mechanical Thrombectomy at Older Age and Histological Analysis of Thrombus Composition
Table 1
Comparison of baseline characteristics and procedural and outcome measures in patients aged <72 years and those aged ≥72 years.
Baseline characteristics
Age (years)
Age (years)
Test summary
<72 ()
≥72 ()
Sex (female)
48 (27.6%)
83 (64.8%)
0.0001
Age, years (SD)
61.94 (7.51)
79.50 (4.59)
0.0001
NIHSS on admission, median (range)
13.82 (4.70)
15.28 (4.39)
0.006
Location
Anterior circulation
136 (78.2%)
111 (86.7%)
0.057
Posterior circulation
38 (21.8%)
17 (13.3%)
IV tPA
74 (42.5%)
41 (32.0%)
0.063
Vascular risk factors
Hypertension
106 (60.9%)
90 (70.3%)
0.091
Diabetes mellitus
42 (24.1%)
29 (22.7%)
0.764
Atrial fibrillation
65 (37.4%)
78 (60.9%)
0.0001
Coronary heart disease
17 (9.8%)
26 (20.3%)
0.010
Laboratory findings
Hemoglobin
129.47 (19.19)
118.30 (20.26)
0.0001
WBC, mean (SD)
9.03 (2.96)
9.41 (4.41)
0.366
Neutrophilic
8.28 (7.92)
8.29 (7.22)
0.365
Lymphocyte
1.51 (3.41)
1.22 (1.60)
0.365
NLR
9.23 (7.23)
9.69 (8.75)
0.614
98 (56.3%)
74 (57.8%)
0.796
C-reactive protein, mean (SD)
20.60 (37.81)
21.21 (33.94)
0.883
Fibrinogen (SD)
2.82 (0.83)
3.11 (0.92)
0.006
D-Dimer, mean (SD)
3.29 (7.45)
3.96 (5.58)
0.397
Median onset-to-groin time, min (SD)
300.85 (544.50)
268.95 (138.11)
0.518
Median time from symptom onset to vascular recanalization, min (SD)
328.11 (172.76)
335.60 (152.71)
0.697
Outcome
Reperfusion after endovascular intervention TICI (2b/3)
159.76 (8%)
109 (85.2%)
0.239
ICH
57 (32.8%)
43 (33.6%)
0.879
Clinical outcome mRS score (0–2)
82 (47.4%)
36 (28.1%)
0.001
Mortality
26 (15.0%)
36 (28.1%)
0.005
NIHSS: National Institute of Health Stroke; IV tPA: intravenous recombinant tissue-type plasminogen activator; NLR: neutrophil-to-lymphocyte ratio; TICI: thrombolysis in cerebral infarction; ICH: intracerebral hemorrhage; WBC: white blood cell.
