Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Cancer type</td><td class="align_center">Mechanism</td><td class="align_center">Signalling pathway</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Lymphoma cell [<a href="/journals/omcl/2020/8825387/#B60" target="_blank">60</a>]</td><td class="align_center">↓ c-FLIP, cyclin D1, cMyc</td><td class="align_center">PI3K/AKT/mTOR/STAT3</td></tr><tr><td class="align_left">Ovarian cancer [<a href="/journals/omcl/2020/8825387/#B62" target="_blank">62</a>]</td><td class="align_center">↓ Cyclin D1, DNA-PK, phosphohistone H3<br/>↑ p21</td><td class="align_center">—</td></tr><tr><td class="align_left">Breast cancer [<a href="/journals/omcl/2020/8825387/#B63" target="_blank">63</a>]</td><td class="align_center">↑ Caspase-3-8, p53, p21</td><td class="align_center">STAT3</td></tr><tr><td class="align_left">Lung cancer [<a href="/journals/omcl/2020/8825387/#B27" target="_blank">27</a>]</td><td class="align_center">↓ Survivin<br/>↑DR5</td><td class="align_center">AKT-survivin</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Effects of quercetin on apoptosis of different tumour cells and its mechanism.</div>

Oxidative Medicine and Cellular Longevity

tab5

Table 5

Table 5: Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine 