Review Article
Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine
Table 5
Effects of quercetin on apoptosis of different tumour cells and its mechanism.
| Cancer type | Mechanism | Signalling pathway |
| Lymphoma cell [60] | ↓ c-FLIP, cyclin D1, cMyc | PI3K/AKT/mTOR/STAT3 | Ovarian cancer [62] | ↓ Cyclin D1, DNA-PK, phosphohistone H3 ↑ p21 | — | Breast cancer [63] | ↑ Caspase-3-8, p53, p21 | STAT3 | Lung cancer [27] | ↓ Survivin ↑DR5 | AKT-survivin |
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