Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts

<div>PAC suppressed Dex-induced apoptosis in osteoblasts. (a–d) Expression levels of cleaved caspase-3, Bcl-2, and Bax in the differentially treated osteoblasts. (e) Representative fluorescence images showing coculture with PAC (1 <i>μ</i>M) reduced Dex-induced osteoblast apoptosis. (f) Caspase-3 activity in the differentially treated osteoblasts. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts 

Figure 2 | Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts 