Oxidative Medicine and Cellular Longevity / 2020 / Article / Fig 1

Research Article

ZNRD1 and Its Antisense Long Noncoding RNA ZNRD1-AS1 Are Oppositely Regulated by Cold Atmospheric Plasma in Breast Cancer Cells

Figure 1

Induction of opposite expression of ZNRD1 and ZNRD1-AS1 under different CAP conditions. (a) Schematic structure of ZNRD1 and ZNRD1-AS1 on chromosome. ZNRD1 is indicated by the blue line, with its promoter in green. ZNRD1-AS1 is indicated by the red line. The arrowheads are the transcription direction of each gene. The location of the CpG hypermethylated by CAP is indicated with a red vertical dotted line. (b, c) Expression of ZNRD1 and7 ZNRD1-AS1 was examined by qPCR after treatment of MCF-7- cells with CAP at the indicated doses. The CAP treatment was performed multiple times, with each time in triple culture dishes. The overall average is indicated on the right with . , .

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