ZNRD1 and Its Antisense Long Noncoding RNA ZNRD1-AS1 Are Oppositely Regulated by Cold Atmospheric Plasma in Breast Cancer Cells
DNA methylation and expression profile of ZNRD1 and ZNRD1-AS1 in breast cancer. (a) The methylation level of the specific CpG (CpG ID; cg02078039) at ZNRD1 promoter in breast cancer tissues, which was hypermethylated by CAP in MCF-7, was examined using the data retrieved from the TCGA Wanderer database. No significant difference was found between the normal and cancer tissues. Expression of ZNRD1 (b) and ZNRD1-AS1 (c) was analyzed for tissues in the database GEPIA. Upregulation of ZNRD1 and downregulation of ZNRD1-AS1 were observed in breast cancer tissues. : sample number.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.