Research Article

Transcriptomic Analysis Reveals the Protection of Astragaloside IV against Diabetic Nephropathy by Modulating Inflammation

Figure 7

AS-IV treatment minimizes the COL4 and FN deposition in the kidney of DN rats. The levels of COL4 and FN in the kidney from individual rats were tested by immunohistochemistry and Western blot. (a) Immunohistochemistry analysis of the levels of COL4 and FN in the kidney of individual rats using specific anti-COL4 or anti-FN. (b) Western blot analysis of the levels of COL4 and FN in the kidney of individual rats. Data are representative images (magnification ×400) or expressed as the of each group () from three separate experiments. vs. the NC group. # vs. the DN group. Red arrow: mesangial region. Green arrow: renal interstitium. Yellow arrow: basement membrane.
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