Effects of the Insulted Neuronal Cells-Derived Extracellular Vesicles on the Survival of Umbilical Cord-Derived Mesenchymal Stem Cells following Cerebral Ischemia/Reperfusion Injury
Identification and characterization of EVs derived from N2A cells. (a) Representative image of EVs by transmission electron microscopy (TEM) scale bar, 200 nm and 100 nm. (b) The size distribution of EVs by nanosight tracking analysis (NTA). (c) Western blotting analysis of EVs markers in supernatant (Sup), EVs, and whole cellular lysis (WCL). (d) The concentration of EVs from N2A cells conditioned medium upon non-OGD/R condition and OGD/R24H insult as evaluated by NTA. All data are presented as the ().;. non-OGD/R group compared with OGD/R24H group.
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