Buyang Huanwu Decoction Enhances Revascularization via Akt/GSK3β/NRF2 Pathway in Diabetic Hindlimb Ischemia

Figure 2

BHD increases tissue perfusion and angiogenesis. (a, b) The tissue perfusion level of the hindlimbs in the HLI mice after 0, 7, and 14 days of BHD treatment (). (c) Micro-CT imaging of tissue vessels in hindlimbs of HLI mice (). (d, e) The protein expression level and quantitative analysis of VEGFA after 14 days of BHD treatment (). (f) Angiogenesis in the ischemic area of the hindlimbs in HLI mice after 14 days of BHD treatment (). . NS, , compared with HLI+NS group; and , compared with HLI+NS group.

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