ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress
The protein and mRNA expressions of retinal SIRT1 and ALDH2 detected by immunofluorescence, RT-PCR, and Western blotting in the CON, T1DM, and T2DM groups after a 12-week study: (a) the representative immunofluorescence picture of ALDH2 and SIRT1; (b) the relative mRNA expression of ALDH2; (c) the relative mRNA expression of SIRT1; (d) the representative Western blotting picture of ALDH2 and SIRT1; (e) the relative protein expression of ALDH2; (f) the relative protein expression of SIRT1. Scale bar: 100 μm. Values are presented as ,-4. ,, and : the T1DM group and the T2DM group vs. the CON group; #,##, and ###: the T2DM group vs. the T1DM group.
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