ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress

Figure 5

The expressions of retinal VEGF-α, HIF-1α, and VEGFR2 in the CON, T1DM, and T2DM groups after a 12-week study: (a, d) the representative immunofluorescence picture of VEGF-α, HIF-1α, and VEGFR2; (b) the relative expression of VEGFR2; (c) the relative expression of HIF-1α; (e) the representative Western blotting picture of VEGF-α, HIF-1α, and VEGFR2; (f–h) the relative protein expression of VEGF-α, HIF-1α, and VEGFR2. Scale bar: 100 μm. Values are presented as , -4. , , and : the T1DM group and the T2DM group vs. the CON group; ^#, ^##, and ^###: the T2DM group vs. the T1DM group.

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