ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress

<div>The levels of retinal SOD1, NOX4, total ROS, and mtDNA damage in the CON, T1DM, and T2DM groups after a 12-week study: (a) the representative immunofluorescence picture of SOD1 and NOX4; (b) SOD1 immunofluorescence levels normalized to CON; (c) NOX4 immunofluorescence levels normalized to CON; (d) the retinal total ROS level; (e) damage of mtDNA in the retina. Scale bar: 100 <i>μ</i>m. 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27V0H384Z"></path></g></svg>:</span> the T2DM group vs. the T1DM group.</div>

Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress 