Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells

Figure 1

Bavachin inhibits osteosarcoma (OS) cell viability. (a) Chemical structure of bavachin. (b) CCK8 assay shows bavachin inhibits OS cells in a concentration- (5 μM, 10 μM, 20 μM, 40 μM, and 80 μM) and time- (24 h, 48 h, and 72 h) dependent manner. (c) Morphologic features of OS cells on microscopy. Cells became round and showed shrunk after bavachin (10 μM, 20 μM, and 40 μM) treatment for 24 h.

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