Research Article

Pharmacological Activation of Nrf2 by Rosolic Acid Attenuates Endoplasmic Reticulum Stress in Endothelial Cells

Figure 3

Effect of Rosolic acid on level of Nrf2 gene expression (a) by qRT-PCR analysis and protein level (b) by western blotting in ER stress-induced EA.hy926 cells. (c) The effect of Rosolic acid on Nrf2 translocation from cytosol to the nucleus by western blotting in EA.hy926 cells under ER stress. Data are represented as of three independent experiments. Significant compared with the control group. #Significant compared with TPG group; determined by one-way ANOVA followed by Tukey’s post hoc test (0, control; TPG, thapsigargin; 2.5, 5, 10, and 25, concentrations of Rosolic acid in μM).
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