Research Article

Pharmacological Activation of Nrf2 by Rosolic Acid Attenuates Endoplasmic Reticulum Stress in Endothelial Cells

Figure 4

Effect of Rosolic acid on Nrf2 downstream targets such as (a) catalase (CAT), (b) glutathione peroxidase (GPx), (c) heme oxygenase-1 (HO-1), and (d) NAD(P)H: quinone-oxidoreductase-1 (NQO-1) expression in ER stress-induced EA.hy926 cells by qRT-PCR analysis. Data are represented as of three independent experiments. Significant compared with Control group. #Significant compared with TPG group; determined by one-way ANOVA followed by Tukey’s post hoc test (0, control; TPG, thapsigargin; 2.5, 5, 10, and 25, concentrations of Rosolic acid in μM).
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