Antioxidant Activities of Commiphora leptophloeos (Mart.) J. B. Gillett) (Burseraceae) Leaf Extracts Using In Vitro and In Vivo Assays

Table 1

Data obtained from KEGG using the rutin, vitexin, and quercetin diglycosides as target after the overlap analysis.

KEGG Brite (Homo sapiens)	Adjusted value	Corrected value	Related genes (targets)
Immune system	6.61-19	1.22-16	PTGS2; CASP3; CXCL8; IL6; TNF; MAPK7; HSP90AA1; IL1B; RELA
Cardiovascular disease	7.83-09	7.62-08	RELA; HSP90AA1; IL1B; TNF; MAPK7; IL6; CXCL8;
Infectious disease bacterial	2.27-12	1.05-10	CASP3; CXCL8; IL6; TNF; IL1B; RELA
Infectious disease viral	4.03-10	6.77-09	PRSS1; CASP3; CXCL8; IL6; TNF; IL1B; RELA; PTGS2; PIK3CG
Infectious disease parasitic	1.83-09	2.37-08	IL6; CXCL8; IL1B; TNF; RELA
Neurodegenerative disease	8.18-07	4.32-06	IL6; IL1B; SOD1; TNF; CASP3
Pathways in cancer	5.16-09	5.30-08	PTGS2; CASP3; CXCL8; IL6; PPARG; HSP90AA1; RELA
Nervous system	2.52-05	8.48-05	PTGS2; PTGS1; CASP3
Metabolic pathways	1.42-08	1.19-07	PTGS2; PTGS1; PIK3CG; AR; ETNK2; ETNK1; CAT; CHKA; CHKB
Lipid metabolism	1.65-07	1.05-06	ETNK1; CHKA; CHKB; ETNK2
Development and regeneration	4.8-07	2.71-06	PPARG; IL1B; TNF; RELA
Cell growth and death	4.11-05	0.000135	RELA; TNF; CASP3; IL6; CXCL8; RELA; HSP90AA1; IL1B
Transcription misregulation in cancer	2.07-06	1.00-05	IL6; CXCL8; RELA; PPARG
Cancer	1.36-05	5.24-05	PTGS2; RELA; CASP3