Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats
Table 2
KEGG pathway enrichment of the differential expressed genes involved in amino acid and lipid metabolism between the HFD and HFD+CGA groups.
Serial
Pathway
DEGs
value
value
Pathway ID
4
Glycine, serine, and threonine metabolism
6/42
0.00004
0.00228
ko00260
6
Steroid biosynthesis
4/26
0.00065
0.02269
ko00100
7
Cysteine and methionine metabolism
5/58
0.00205
0.06087
ko00270
8
Valine, leucine, and isoleucine biosynthesis
2/5
0.00234
0.06087
ko00290
9
Linoleic acid metabolism
4/41
0.00370
0.08540
ko00591
11
Glycerophospholipid metabolism
6/106
0.00626
0.11017
ko00564
12
Phenylalanine, tyrosine, and tryptophan biosynthesis
2/8
0.00636
0.11017
ko00400
18
Arachidonic acid metabolism
6/119
0.01079
0.12472
ko00590
25
Alanine, aspartate, and glutamate metabolism
3/41
0.02574
0.21416
ko00250
30
Arginine biosynthesis
2/23
0.04930
0.33080
ko00220
31
Phenylalanine metabolism
2/23
0.04930
0.33080
ko00360
37
Bile secretion
4/95
0.06103
0.34306
ko04976
KEGG pathway enrichment of the differential expressed genes involved in amino acid and lipid metabolism between the HFD and HFD+CGA groups. Notice: we just showed the value is equal or smaller than 0.05 about the pathway of amino acid and lipid metabolism, and bile secretion.