Polygonum cuspidatum Extract Exerts Antihyperlipidemic Effects by Regulation of PI3K/AKT/FOXO3 Signaling Pathway

Figure 8

Effects of PCE on the PI3K-AKT signaling pathway and its downstream factors FOXO3 and ERα in OA-induced HepG2 cells. (a) The effect of PCE on the FOXO3 in HepG2. Under a laser confocal microscope (200x), the fluorescence intensity was detected with DAPI (blue) and FOXO3 antibody (green). (b) The effect of PCE on the expression of PI3K and p-PI3K, ERα, AKT, and p-AKT in HepG2. Western blot analysis results.

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