Research Article

Phenolic Compounds of Red Wine Aglianico del Vulture Modulate the Functional Activity of Macrophages via Inhibition of NF-κB and the Citrate Pathway

Figure 3

RWP significantly restored expression of AnxA1 in LPS-induced inflammation. Primary human monocytes were incubated with RWP 20 μg/mL or RWP 200 μg/mL and activated with 1 μg/mL LPS. Expression of AnxA1 (a) and FPR2 (b) was assessed following 24 h treatment with LPS. Protein expression was quantified by using optical density (O.D.) ratio for AnxA1 or FPR2 versus β-actin; normalized values obtained are reported under western blot images. C: control; L: LPS; R20: RWP 20 μg/mL; R200: RWP 200 μg/mL.
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