Walnut Supplementation Restores the SIRT1-FoxO3a-MnSOD/Catalase Axis in the Heart, Promotes an Anti-Inflammatory Fatty Acid Profile in Plasma, and Lowers Blood Pressure on Fructose-Rich Diet

Table 1

Effects of fructose-rich diet and walnut supplementation on total body mass, relative heart mass, and blood pressure in experimental rats.

	C	CW	F	FW	Two-way ANOVA
					W	F
Total body mass (g)					<0.001	<0.01	NS
Heart mass/total body mass (×100)					<0.01	NS	NS
SBP (mm·hg)					<0.05	NS	<0.01
DBP (mm·hg)					NS	NS	NS
HRF (beats/min)					<0.01	NS	NS
MAP (mm·hg)					NS	NS	NS
PP (mm·hg)					NS	NS	NS

Data are presented as for 9 animals per group. A value of was considered as statistically significant. C: animals on standard laboratory chow; CW: animals on standard laboratory chow and walnut supplementation; F: animals fed a fructose-rich diet; FW: fructose-fed animals on walnut supplementation; SBP: systolic blood pressure; DBP: diastolic blood pressure; HRF: heart rate frequency; MAP: mean arterial pressure; NS: not significant. Significantly different from control, walnuts, and ^$fructose. Significance is , , and .