Oxidative Medicine and Cellular Longevity / 2021 / Article / Fig 3

Research Article

Physiological Dose of EGCG Attenuates the Health Defects of High Dose by Regulating MEMO-1 in Caenorhabditis elegans

Figure 3

EGCG exerts its biochemical function through regulating ROS. (a) Antioxidants mitigate health indicator of C. elegans after high-dose EGCG stress at day 4 of adulthood. Scale bar: 200 μm. (b) Estimation body size per worm treated with antioxidants, three replicate experiments; worms. , , and , by two-way ANOVA. (c) Number of thrashes per minute in liquid. Three replicate experiments; worms. , , and , by two-way ANOVA. (d) Survival rate changes in the lifespan of N2 worms, where the larvae were treated with high dose of EGCG and then was treated with high dose of EGCG combined with DTT during adulthood. , by two-way ANOVA. (e) Relative quantification of Mitosox of worm treatment with EGCG at day 0, day 2, and day 4. , by two-way ANOVA. (f) Representative images of Mitosox reporter worms treated with vehicle or EGCG, showing quality of mitochondria ROS following. Scale bar: 200 μm. (g) Relative quantification of Mitosox of worm treatment with EGCG at day 0 and day 2 of adulthood, where the larvae are treated with physiologic doses of EGCG and then was treated with high doses of EGCG during adulthood. , by two-way ANOVA.
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