Oxidative Medicine and Cellular Longevity / 2021 / Article / Fig 4

Research Article

Physiological Dose of EGCG Attenuates the Health Defects of High Dose by Regulating MEMO-1 in Caenorhabditis elegans

Figure 4

EGCG activates NADPH redox feedback signaling through moderate inhibition of MEMO-1. (a) Survival rate changes in the lifespan of EGCG extended lifespan in the memo-1(gk345) mutants. (b) Survival rate changes in the lifespan of EGCG extended lifespan in the bli-3(e767) mutants. (c) Relative quantification of Pmemo-1::GFP of worm treatment with EGCG at day 0. , , , and , by two-way ANOVA. (d) Relative quantification of Pmemo-1::GFP of worm treatment with EGCG at day 2 and day 4. , , , and , by two-way ANOVA. (e) Representative images of Pmemo-1::GFP reporter worms treated with EGCG at day 2 and day 4, showing quality of MOME-1 following, Scale bar: 200 μm. (f) Estimation body size per memo-1(gk345) mutants in treated with EGCG, three replicate experiments; worms. , , and , by two-way ANOVA. (g) Representative images of memo-1(gk345) mutants treated with EGCG at day 2 and day 4. Scale bar: 200 μm.
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