Research Article
Serum Interleukin-37 Increases in Patients after Ischemic Stroke and Is Associated with Stroke Recurrence
Table 1
Baseline characteristics of 310 stroke patients.
| | Ischemic stroke patients |
| | Age, medians (IQRs) (years) | 66 (56-75) | | Sex-female ( (%)) | 180 (58.1) | | BMI, medians (IQRs) (kg/m2) | 25.5 (23.9-26.8) | | Vascular risk factors ( (%)) | | | Hypertension | 199 (64.2) | | Diabetes | 101 (32.6) | | Hypercholesterolemia | 109 (35.2) | | Atrial fibrillation | 36 (11.6) | | Cardiovascular diseases | 59 (19.0) | | TIA | 28 (9.0) | | Family history of stroke | 21 (6.8) | | Smoking | 66 (21.3) | | Drinking | 59 (19.0) | | Prestroke treatment ( (%)) | | | Antihypertensive | 162 (52.3) | | Hypoglycemic | 81 (26.1) | | Anticoagulants | 26 (8.4) | | Antiplatelet agents | 77 (24.8) | | Acute treatment ( (%)) | | | TPA-T | 32 (10.3) | | Mechanical thrombectomy | 11 (3.5) | | TPA-T and/or mechanical thrombectomy | 38 (12.3) | | Stroke etiology no. (%) | | | Small-vessel occlusive | 68 (21.9) | | Large-vessel occlusive | 90 (29.0) | | Cardioembolic | 106 (34.2) | | Other | 30 (9.7) | | Unknown | 16 (5.2) | | NIHSS score at admission, medians (IQRs) | 6 (3-11) | | | 141 (45.5) | | Lesion volumes at admission (), median (IQR) (ml) | 15 (5-31) | | Laboratory findings at admission, medians (IQR) | | | Il-37 (pg/ml) | 344.1 (284.4-405.3) | | Il-6 (ng/ml) | 12.8 (9.2-16.9) | | CRP (mg/l) | 5.5 (2.4-9.3) | | FSG (mmol/l) | 5.81 (5.21-6.33) | | Follow-up at 3-month | | | mRS score, medians (IQR) | 1 (0-2) | | | 81 (26.1) | | Stroke recurrence ( (%)) | 36 (11.6) |
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IQR: interquartile range; BMI: body mass index; NIHSS: National Institutes of Health Stroke Scale; TPA-T: tissue plasminogen activator-treated; CRP: C-reactive protein; IL-37: interleukin-37; IL-6: interleukin-6; FSG: fasting serum glucose; mRS: modified Rankin scale.
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