Bioactive Compounds of Raspberry Oil Emulsions Induced Oxidative Stress via Stimulating the Accumulation of Reactive Oxygen Species and NO in Cancer Cells

Table 4

Statistically significant correlation coefficients between DNA damage and levels of reactive oxygen species (ROS) and nitric oxide (NO).

Cell line	Oil type	ROS level vs. DNA damage	NO level vs. DNA damage
LoVo	ROSCO2	0.52	0.87
	ROCOP	0.89	0.7
LoVo/DX	ROSCO2	-0.34	0.76
	ROCOP	0.32	0.7
MCF7	ROSCO2	0.5	0.61
	ROCOP	-0.29	0.52
MCF7/DX	ROSCO2	0.64	0.72
	ROCOP	0.56	0.71
A549	ROSCO2	-	-0.36
	ROCOP	0.64	0.76

LoVo: colon adenocarcinoma cell line; LoVo/DX: doxorubicin-resistant colon adenocarcinoma cell line; MCF7: breast cancer cell line; MCF7/DX: doxorubicin-resistant breast cancer cell line; A549: lung cancer cell line; ROSCO2: raspberry oil extracted by supercritical CO2; ROCOP: raspberry oil cold-pressed.