Review Article
A Literature-Based Update on Benincasa hispida (Thunb.) Cogn.: Traditional Uses, Nutraceutical, and Phytopharmacological Profiles
Table 3
Antimicrobial, anthelmintic, and larvicidal effects of different parts or their extracts/fractions or isolated compounds.
| | Extract/isolated compounds | Dose/concentration model (in vitro/in vivo) | Results/mechanisms | References |
| | Antimicrobial effects | | Methanolic whole plant extract | Pseudomonas aeruginosa
Vibrio parahaemolyticus
In vitro
Standard: DMSO |
| [70] | | Hispidalin | Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella enterica;
Fungi: Penicillium chrysogenum, Fusarium solani, Aspergillus flavus, Colletotrichum gloeosporioides
In vitro
Standard: acetoin (0.01–20 μg/μl) | Antibacterial: ,
Antifungal: | [59] | | Aqueous peel extract | Staphylococcus aureus, Micrococcus luteus, Escherichia coli, Klebsiella pneumoniae
In vitro
Standard: DMSO 150 μL | Antibacterial: | [11] | | Anthelmintic effect | | Ethanolic seed extract | Pheretima posthuman/in vitro
Standard: phenytoin sodium | , 40, and 60 mg
Dose-dependent anthelmintic effect | [72] | | Larvicidal effect | | Phloem lectin-like protein from the exudate | Samia ricini larvae/in vitro
Standards: Precision Plus Protein™, serum albumin | ↑ inhibitory activity against the larvae
Dose: 70 μg/g | [46] |
|
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Abbreviations: IC50: value concentration that inhibits cell growth by 50%; MIC: minimum inhibitory concentration.
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