Research Article
The Association of Polymorphisms in Nrf2 and Genes Involved in Redox Homeostasis in the Development and Progression of Clear Cell Renal Cell Carcinoma
Table 2
Nrf2, SOD2, GPX1, and GSTP1 genotypes in relation to the risk of ccRCC.
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aOR: odds ratio adjusted for age, gender, BMI, pack-years, and hypertension; CI: confidence interval; breference group; cC/C: carriers of both referent alleles; dC/A and A/A: carriers of at least one variant allele; eAla/Ala: carriers of both referent alleles; fAla/Val and Val/Val: carriers of at least one variant allele; gPro/Pro: carriers of both referent alleles; hPro/Leu and Leu/Leu: carriers of at least one variant allele; iIle/Ile: carriers of both referent alleles; jIle/Val and Val/Val: carriers of at least one variant allele; kAla/Ala: carriers of both referent alleles; lAla/Val and Val/Val: carriers of at least one variant allele; m(Ile/Ile) (Ala/Ala): carriers of both referent alleles for rs1695 and rs1138272; n(Ile/Ile) (Ala/Val+Val/Val): carriers of both referent alleles for rs1695 and at least one variant allele rs1138272; o(Ile/Val+Val/Val) (Ala/Ala): carriers of at least one variant allele for rs1695 and both referent alleles for rs1138272; p(Ile/Val+Val/Val) (Ala/Val+Val/Val): carriers of at least one variant allele for both rs1695 and rs1138272; qNA: not applicable. |