Research Article

Follistatin-Like 1 Attenuation Suppresses Intervertebral Disc Degeneration in Mice through Interacting with TNF-α and Smad Signaling Pathway

Figure 2

FSTL-1-knockdown mice expressed a lower level of cartilage degeneration and suppressed disc degeneration. (a) Safranin O staining of IVD tissues in the different groups. CON: normal discs. WT: degenerative discs of WT mice. FSTL-1+/-: degenerative discs of FSTL-1-knockdown mice. Magnification ×200. . (b) Quantitative analysis of the cartilage area based on Safranin O staining. (c) Representative image of HE staining of IVDs in the different groups. Magnification ×200. . .
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