Research Article

Antioxidant and Anti-inflammatory Effect of Cannabidiol Contributes to the Decreased Lipid Peroxidation of Keratinocytes of Rat Skin Exposed to UV Radiation

Figure 5

The level of NFκB subunits (p52 and p65) as well as product of its transcriptional activity (TNFα) in the keratinocytes of the skin of control rats, as well as rats’ skin for 4 weeks exposed every 48 hours to UVA (dose increased from 0.5 to 5 J/cm2) or UVB radiation (dose increased from 0.02 to 2 J/cm2) and/or every 12 hours to the action of CBD (2.5% ). The mean values for six rats in each group ± SD are shown as follows: a—differences vs. control group, (a, ; a, ); x—differences vs. UVA-treated group, (x, ; x, ); y—differences vs. UVB-treated group, (y, ; y, ).