Research Article

Integrated Analysis to Identify a Redox-Related Prognostic Signature for Clear Cell Renal Cell Carcinoma

Figure 10

Cox regression analysis was performed on the common clinical characteristics and RRG-based signature in the TCGA cohort, and the establishment and verification of the nomogram. (a) Univariate Cox regression analysis of correlations between risk score for OS and clinical characteristics. (b) Multivariate Cox regression analysis of correlations between risk score for OS and clinical characteristics. (c) Nomogram for predicting the 1-year, 3-year, and 5-year OS of ccRCC patients in the TCGA cohort. (d, e, f) Calibration curves of the nomogram to predict OS at 1, 3, and 5 years. (g) Kaplan-Meier survival curve analysis of OS in the high- and low-risk subgroups of the TCGA cohort based on the nomogram. (h) Time-dependent ROC curves for predicting OS in the TCGA cohort based on the nomogram. The ROC curves and AUC were shown to predict ccRCC patients at 1, 3, and 5 years. (i) Kaplan-Meier survival curve analysis of OS in the high- and low-risk subgroups of the E-MTAB-1980 cohort based on the nomogram. (j) Time-dependent ROC curves for predicting OS in the E-MTAB-1980 cohort based on the nomogram. The ROC curves and AUC were shown to predict ccRCC patients at 1, 3, and 5 years.
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