Predictors of Mortality in Critically Ill COVID-19 Patients Demanding High Oxygen Flow: A Thin Line between Inflammation, Cytokine Storm, and Coagulopathy
Table 1
Characteristics of patients admitted to ICU with moderate to severe ARDS due to COVID-19-related pneumonia, overall and subpopulation analysis according to survival.
Total ()
ICU patients
Live ()
Dead ()
Gender, (%)
Male
110 (68.8)
47 (73.4)
63 (65.6)
0.384
Female
50 (31.3)
17 (26.6)
33 (34.4)
Age,
<0.001
Laboratory at admission to hospital, median (IQR)
CRP
81.2 (53.8–173.4)
74.7 (46.7–117.5)
105.2 (58.1–200.5)
0.008
Lymphocytes
0.74 (0.53–1.04)
0.84 (0.56–1.36)
0.66 (0.46–0.86)
0.001
D-dimer
881 (523–2660)
646 (372–1582)
1051 (650–3642)
0.004
Ferritin
875 (497–1482)
850 (516–1521)
891 (484–1482)
0.794
Thrombocytes
235 (177–329)
247 (200–345)
228 (159–302)
0.096
INR
1.13 (1.01–1.30)
1.12 (0.99–1.28)
1.14 (1.04–1.34)
0.130
PT
87 (69–100)
90 (72–103)
86 (68–99)
0.325
APTT
25.2 (21.9–29–8)
24.1 (21.4–28.0)
26.1 (22.7–30.2)
0.077
Fibrinogen
3.9 (3.4–4.9)
4.0 (3.5–4.8)
3.8 (3.2–4.9)
0.605
Laboratory at admission to ICU, median (IQR)
CRP
87.8 (51.5–173.3)
78.4 (52.3–148.9)
95.1 (50.7–195.9)
0.166
Lymphocytes
0.63 (0.44–0.88)
0.7 (0.49–0.99)
0.61 (0.38–0.81)
0.019
D-dimer
1414 (701–5030)
1027 (566–2585)
1944 (860–7423)
0.001
Ferritin
1108 (485–1698)
1181 (625–1640)
1058 (454–1764)
0.947
Thrombocytes
191 (150–278)
191 (151–259)
195 (149–291)
0.668
Serum albumin
31 (29–34)
35 (33–37)
29 (27–31)
<0.001
INR
1.15 (1.05–1.29)
1.13 (1.01–1.28)
1.16 (1.08–1.35)
0.087
PT
89 (72–103)
96 (74–108)
86 (69–99)
0.115
APTT
25.9 (23.1–28.5)
25.4 (22.7–27.6)
26.1 (23.3–29.8)
0.272
Fibrinogen
4.3 (3.6–5.3)
4.4 (3.7–5.4)
4.2 (3.6–5.2)
0.744
IL6
91 (38.80–286.00)
50.42 (24.45–100.90)
133.80 (74.00–426.80)
<0.001
CT score
20 (16–23)
19 (16–22)
21 (19–23)
0.017
From beginning of symptoms to hospital admission (days), median (IQR)
7 (4–9)
7 (5–9)
7 (4–10)
0.844
From beginning of symptoms to IUC admission (days), median (IQR)
