PAR2 Deficiency Induces Mitochondrial ROS Generation and Dysfunctions, Leading to the Inhibition of Adipocyte Differentiation

Figure 1

Impairment of adipogenesis in PAR2 KO mice. Tissues were isolated from 5-week-old WT and PAR2 KO male mice. (a) Body weight of WT and PAR2 KO mice (). (b) The organ-to-body weight ratio was calculated to observe differences in the development of tissues between WT and PAR2 KO mice. Representative H&E staining images of (c) sWAT and (d) eWAT of WT and PAR2 KO mice (/group). (e) qPCR was performed to measure mRNA expression levels of adipogenesis and lipolysis markers in sWAT (/group). Data are expressed as the . , , and compared to WT.

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