PAR2 Deficiency Induces Mitochondrial ROS Generation and Dysfunctions, Leading to the Inhibition of Adipocyte Differentiation

Figure 2

PAR2 deficiency impairs adipocyte differentiation. Preadipocytes were isolated from sWAT of male WT and PAR2 KO mice (aged 5 weeks). Cells were differentiated into adipocytes for 7 days. (a) Representative microscopic images of primary-cultured adipocytes are shown. (b) qPCR was performed using primary-cultured adipocytes to measure mRNA expression levels of genes associated with adipocyte differentiation (/group). (c) Oil Red O staining images of primary-cultured adipocytes with or without GB83 treatment (). Data are expressed as the . , , and compared to WT.

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