Tea Polyphenol Attenuates Oxidative Stress-Induced Degeneration of Intervertebral Discs by Regulating the Keap1/Nrf2/ARE Pathway

<div>TP delays the intervertebral disc degeneration in vivo via the Nrf2/KEAP/ARE pathway. (a) MRI test of rat caudal discs reveals the protective role of TP in intervertebral disc degeneration. (b) Pfirrmann grade showed the significant protective role of TP. (c) Histological analysis of caudal discs. (d) Histological grading test. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Tea Polyphenol Attenuates Oxidative Stress-Induced Degeneration of Intervertebral Discs by Regulating the Keap1/Nrf2/ARE Pathway 