Effects of Fluorine on Neutrophil Extracellular Trap Formation through Regulating AMPK/p38 Signaling Pathway

Figure 1

Visualization of DNA decorated with histones (H3) and neutrophil elastase (NE) in NaF induced NET structures. Neutrophils were stimulated with NaF (1 mM) or PBS (control group). And the formation of NETs was determined by fluorescence confocal microscopy. (b, e, h, k) show DNA. (a, g) show H3. (d, j) show MPO. (c) which is merged from (a, b) shows H3 in PBS-induced network structures. (f) which is merged from (d, e) shows MPO in PBS-induced network structures. (i) which is merged from (g, h) shows H3 in NaF- (1 mM) induced network structures. (l) which is merged from (j, k) shows MPO in NaF- (1 mM) induced network structures.