Brusatol Inhibits Tumor Growth and Increases the Efficacy of Cabergoline against Pituitary Adenomas

Figure 2

Brusatol (BT) inhibits pituitary tumor growth in xenograft models. (a, d) Representative images of xenograft tumors from mice treated with control vehicle or BT at 24 days of drug administration. (b, e) Tumor volume growth curves of nude mice in different treatment groups. BT inhibited the rate of tumor growth in GH3 and MMQ cells. (c, f) Tumor weights from mice injected with GH3 cells and treated with control vehicle or BT at day 24 of drug administration. Data are represented as the . .

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