Research Article
Deferasirox, an Iron-Chelating Agent, Improves Testicular Morphometric and Sperm Functional Parameters in a Rat Model of Varicocele
Figure 3
DFX administration improves spermatozoa function and integrity in VCL-induced rats: (a) spermatozoa motility, (b) spermatozoa concentration (106/ml), (c1) spermatozoa abnormal morphology, (c2–c4) detailed spermatozoa abnormal morphology (c2: head, c3: neck, and c4: tail), (d) spermatozoa lipid peroxidation, (e) spermatozoa persistent histone content, and (f) spermatozoa DNA damage. Data are presented as . , , and show significant difference between the three experimental groups: control, VCL, and VCL-DFX (VCL rats supplemented with DFX).
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