T0901317, an Agonist of Liver X Receptors, Attenuates Neuronal Apoptosis in Early Brain Injury after Subarachnoid Hemorrhage in Rats via Liver X Receptors/Interferon Regulatory Factor/P53 Upregulated Modulator of Apoptosis/Dynamin-1-Like Protein Pathway

Figure 3

T0901317 attenuated the neurobehavior deficits and the number of cleaved caspase-3/neuron-specific nuclear protein- (NeuN-) positive cells at 24 h after subarachnoid hemorrhage (SAH). (a) Modified Garcia and (b) beam balance scores, per group. Error bars were represented as using Kruskal-Wallis test followed by the Dunn post hoc test. (c) The quantification of double immunofluorescence staining. Error bars were represented with using one-way ANOVA followed by the Tukey post hoc test, per group. (d) Representative double immunofluorescence staining of 3 groups.  μm. ^# vs. Sham group; ^## vs. Sham group; vs. SAH+vehicle group. Vehicle, 30% dimethyl sulfide (DMSO).

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