Research Article

Hydromorphone Protects against CO2 Pneumoperitoneum-Induced Lung Injury via Heme Oxygenase-1-Regulated Mitochondrial Dynamics

Table 1

Patient demographics and characteristics.

IndexHydromorphone ()Morphine () value

Age (years)0.813
Weight (kg)0.145
BMI (kg/m2)0.258
Diagnosis, (%)0.863
Uterine myomas13 (52%)12 (48%)
Ovarian cysts9 (36%)37 (44%)
Endometrial carcinoma2 (8%)1 (4%)
Cervical intraepithelial neoplasia1 (4%)0 (0%)
Ovarian teratomas0 (0%)1 (4%)
Duration of pneumoperitoneum (min)145 (128, 167)145 (130, 170)0.876
Duration of anesthesia (min)171 (160, 209)180 (162, 199)0.884
Recovery time (min)20 (15, 26)20 (15, 28)0.914
Extubation time (min)20 (15, 24)20 (15, 25)0.692
Total fluid intake (ml)1500 (1500, 1600)1500 (1425, 1800)0.705
Bleeding volume (ml)100 (80, 120)100 (100, 175)0.477
Urine volume (ml)350 (275, 450)300 (250, 425)0.465