Research Article

DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice

Table 1

Effects of sepsis score at 8 hours on survival time of mice.

8-week-old mice
LPS dosage15 μg/g-BW20 μg/g-BW30 μg/g-BW

Number101010
BW (g)26.8 (0.9)26.6 (0.9)25.7 (1.4)
Sepsis score10.0 (1.8)9.5 (2.0)17.4 (1.6)
HR1.522.60.95
95% CI on HR1.02, 2.521.37, 6.310.06, 13.92
value0.0390.0120.970

Data are presented as mean (standard deviation). LPS: lipopolysaccharide; BW: body weight; HR: hazard ratio; CI: confidence interval.