Review Article

Antioxidative Potentials of Incretin-Based Medications: A Review of Molecular Mechanisms

Table 1

Two main classes of incretin-based antidiabetic medications.

Approved drugsMechanisms of actionRef.

GLP-1raExenatide (exendin-4), albiglutide, liraglutide, lixisenatide, semaglutide, dulaglutideMimic hypoglycemic influences of incretin hormones[19, 20]
DPP-4iSitagliptin, saxagliptin, vildagliptin, linagliptinIncrease the active circulatory levels of GLP-1[27, 28]