Changes in Key Mitochondrial Lipids Accompany Mitochondrial Dysfunction and Oxidative Stress in NAFLD

Figure 1

Course of metabolic phenotype under the western diet regimen. CD: control diet; WD: western diet. (a) Body weight. (b) Liver weight. (c) Hepatic steatosis. (d) Hepatic fibrosis. (e) ALAT. (f) ASAT. (g) mRNA expression of genes involved in lipid metabolism (Srebf1, Pparα) and inflammation (Tlr9, Tnf-α), from left to right. Data are expressed as ; 2-way ANOVA with a subsequent Bonferroni post hoc test or 2-way ANOVA with rank with Tukey post hoc test; , , and versus control diet; ^$$$ versus weeks of diet. mice per time point and condition.

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