Oxidative Stress in Association with Metabolic Health and Obesity in Young Adults
Table 2
Differences between men and women in terms of biochemical and oxidative stress parameters as well as epidemiologic and anthropometric data.
Variable
Men Mean (SD) ( (%))/median (Q1; Q3)
Women Mean (SD) ( (%))/median (Q1; Q3)
value Mann–Whitney/
Age (years)
27.69 (4.41)
189
27.6374 (4.54)
233
ns
Alcohol (yes)
159 (84%)
189
155 (67%)
232
0.001
Smoking (i) Current vs. (ii) Past (iii) Never
37 (20%) 27 (14%) 125 (66%)
189
39 (17%) 20 (9%) 172 (74%)
231
ns
Family history of premature coronary heart disease (CHD) (yes)
98 (52%)
189
109 (47%)
232
ns
Family history of type 2 diabetes (T2D) (yes)
91 (48%)
189
130 (56%)
232
ns
Total cholesterol (TC) (mmol/L)
4.83 (1.06)
189
4.82 (0.86)
233
ns
Low density lipoprotein cholesterol (LDL-C) (mmol/L)
2.98 (0.96)
189
2.70 (0.81)
233
0.0072
High density lipoprotein cholesterol (HDL-C) (mmol/L)
1.44 (0.35)
189
1.82 (0.44)
232
<0.001
Triglycerides (TG) (mmol/L)
1.32 (1.52)
189
0.91 (0.50)
232
0.00049
Glucose (mmol/L)
5.06 (0.46)
188
4.87 (0.43)
232
<0.001
Uric acid (UA) (μmol/L)
342.63 (64.03)
189
255.67 (55.81)
233
<0.001
Body mass index (BMI) (kg/m2)
25.52 (5.20)
189
22.54 (4.27)
233
<0.001
Systolic blood pressure (SBP) (mmHg)
130.89 (14.64)
189
120.35 (11.79)
233
<0.001
Diastolic blood pressure (DBP) (mmHg)
79.76 (10.58)
189
76.55 (9.45)
233
0.0022
Thiol group concentration (PSH) (μmol/g protein)
4.39 (4.00; 4.70)
189
4.00 (3.60; 4.20)
233
<0.001
Ceruloplasmin (CER) (mg/dL)
36.10 (31.80; 41.40)
189
45.10 (38.70; 55.10)
233
<0.001
Total antioxidant capacity (TAC) (mmol/L)
1.02 (0.950; 1.130)
189
1.04 (0.940; 1.130)
233
0.905
Total oxidative status (TOS) (μmol/L)
4.70 (3.600; 6.100)
189
5.300 (4.40; 6.950)
232
0.0024
Oxidative stress index (OSI) (%)
0.45 (0.36; 0.61)
189
0.51 (0.41; 0.67)
232
0.0034
Lipid hydroperoxides (LPH) (μmol/L)
2.39 (1.90; 3.10)
188
2.50 (2.00; 3.10)
232
0.36
Superoxide dismutase (SOD) (NU/mL)
19.63 (18.44; 21.651)
189
21.10 (19.70; 22.70)
233
<0.001
MnSOD (NU/mL)
10.80 (9.77; 11.90)
189
11.40 (10.10; 12.50)
233
0.0015
CuZnSOD (NU/mL)
9.066 (8.10; 10.30)
189
9.80 (8.60; 11.00)
233
0.00026
Lipofuscin (LPS) (RU/L)
190.30 (114.01; 302.30)
189
275.20 (196.40; 350.20)
233
<0.001
Malondialdehyde (MDA) (μmol/L)
1.66 (1.29; 2.06)
186
1.690 (1.310; 2.110)
233
0.52
Mean (SD): mean value (standard deviation) calculated for quantitative features; (%): the number of people (the percentage of this number in relation to the subgroup) given in the case of qualitative features; : size of the subgroup; MHNW: metabolically healthy normal weight individuals; MHO: metabolically healthy obese individuals; MUO: metabolically unhealthy obese individuals; ns: not significant; Q1: first quartile; Q3: third quartile. test.
