Naringin and Hesperidin Counteract Diclofenac-Induced Hepatotoxicity in Male Wistar Rats via Their Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities

Table 1

Effect of naringin, hesperidin, and their combination on serum biochemical parameters related to liver function in diclofenac-administered rats.

Parameter	Normal control	Diclofenac	Diclofenac+naringin	Diclofenac+hesperidin	Diclofenac+naringin+hesperidin
ALT (U/L)	^c	^a	^ab	^c	^b
AST (U/L)	^b	^a	^b	^b	^b
LDH (U/L)	^c	^a	^b	^b	^b
ALP (U/L)	^c	^a	^b	^ab	^bc
GGT (U/L)	^b	^a	^b	^b	^b
Albumin (g/dL)	^a	^a	^a	^a	^a
Bilirubin (mg/dL)	^b	^a	^b	^b	^b

Data are expressed as the . Number of animals in each group is six. Means, which share different superscript symbols in the same row, are significantly different at .