[Retracted] Novel lncRNA AL033381.2 Promotes Hepatocellular Carcinoma Progression by Upregulating PRKRA Expression

Figure 1

LncRNA-AL033381.2 expression is upregulated in HCC tissues. (a, b) Heatmaps and volcano plots of the differential expressed lncRNAs between LIHC tissues () and normal controls () in TCGA, including the increased levels of AL033381.2. (c) The differential expression of AL033381.2 in the original data of each TCGA RNA-seq sample can be represented by a line graph. The vertical axis is the original data of the expression level of each sample, and the horizontal axis is the cancer tissue and normal tissue of the sample, with one broken line for each sample. (d) The differential expression of AL033381.2 in cancer () and normal tissue samples () can be demonstrated by log₂FC, value, and FDR in the TCGA database. (e) Differential gene expression can also be shown in a histogram. The vertical axis is the log₂FC, and the horizontal axis is different samples, and the log₂FC of each sample is represented by a column diagram. (f) The relative expression of AL033381.2 between HCC samples and corresponding normal tissues was compared by qRT-PCR analysis (). (g) The subcellular location of AL033381.2 in Hep3B and Huh7 cells was determined by FISH analysis after transfection. Nuclei were stained with DAPI. U6 or GAPDH was used as nuclear and cytosolic markers, respectively.

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