Exosomal miR-17-3p Alleviates Programmed Necrosis in Cardiac Ischemia/Reperfusion Injury by Regulating TIMP3 Expression

Figure 2

Exosomal miR-17-3p attenuated H₂O₂-induced programmed necrosis in primary cardiomyocytes in vitro. (a) miR-17-3p expression was measured by qRT-PCR in primary cardiomyocytes treated with peripheral blood exosomes () using U6 as the control gene. (b, c) Necrotic cell death was assessed using PI staining following treatment with peripheral blood exosomes or the miR-17-3p inhibitor (). The representative images show the PI-positive cells (). Data are presented as the ; ; .

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