Exosomal miR-17-3p Alleviates Programmed Necrosis in Cardiac Ischemia/Reperfusion Injury by Regulating TIMP3 Expression

Figure 4

TIMP3 affected H₂O₂-induced programmed necrosis of primary cardiomyocytes and was regulated by miR-17-3p in vitro. (a) Necrotic cell death was assessed using PI staining of H9C2 cells following TIMP3 overexpression or knockdown. (b) The function of TIMP3 in necrotic cell death was identified using a rescue experiment. Representative images show PI-positive cells (). Data are presented as the (); ; ; .

(a)

(b)