Research Article
BACH1: A Potential Predictor of Survival in Early-Stage Lung Adenocarcinoma
Table 1
Demographic and clinical characteristics of early-stage lung adenocarcinoma cases.
| Characteristics | Training cohort (TCGA) | Validation cohort 1 (GSE13213) | Validation cohort 2 (GSE72094) | No. of patients | Percent (%) | No. of patients | Percent (%) | No. of patients | Percent (%) |
| Total no. | 306 | | 92 | | 311 | | Age | <60 | 85 | 27.8 | 32 | 34.8 | 45 | 14.5 | 60-70 | 126 | 41.2 | 18 | 19.6 | 116 | 37.3 | >70 | 95 | 31.0 | 42 | 45.7 | 150 | 48.2 | Gender | Male | 135 | 44.1 | 50 | 54.3 | 141 | 45.3 | Female | 171 | 55.9 | 42 | 45.7 | 170 | 54.7 | Pathologic stage | I | 215 | 70.3 | 79 | 85.9 | 246 | 79.1 | II | 91 | 29.7 | 13 | 14.1 | 65 | 20.9 | Laterality | Left | 119 | 38.9 | — | — | — | — | Right | 183 | 59.8 | — | — | — | — | Unknown | 4 | 1.3 | — | — | — | — | Smoking history | Yes | 254 | 83.0 | 47 | 51.1 | 236 | 75.9 | No | 52 | 17.0 | 45 | 48.9 | 75 | 24.1 | BACH1 expression | High | 103 | 33.7 | 23 | 33.3 | 50 | 19.2 | Low | 203 | 66.3 | 69 | 66.7 | 261 | 80.8 |
|
|