Research Article
Diet-Derived Circulating Antioxidants and Risk of Stroke: A Mendelian Randomization Study
Table 1
Characteristics of diet-derived antioxidants and stroke datasets.
| Exposures | Data source | SNP | -statistic | Sample size | Population |
| Vit. C (ascorbate) | Shin et al. | 10 | 23.67 | 2,085 | European | Vit. E (α-tocopherol) | Shin et al. | 5 | 71.42 | 7,725 | European | Vit. E (γ-tocopherol) | Shin et al. | 7 | 55.22 | 6,226 | European | Carotene | MRC-IEU | 13 | 76.98 | 64,979 | European | Vit. A (retinol) | MRC-IEU | 8 | 136.20 | 62,991 | European | Zinc | Evans et al. | 8 | 40.13 | 2,603 | European | Selenium | Evans et al. | 6 | 49.70 | 2,603 | European | Outcomes | Data source | Studies | Cases/controls | Sample size | Population | Stroke | Meta-analysis | 17 | 40,585/406,111 | 446,696 | European | Ischemic stroke | Meta-analysis | 17 | 34,217/406,111 | 440,328 | European |
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Vit: vitamin; SNP: single-nucleotide polymorphism.
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