Application of Adsorptive Blood Purification Techniques during Cardiopulmonary Bypass in Cardiac Surgery

Table 1

Main details of membranes and cartridges.

	AN69	AN69ST	PMMA	oXiris	PMX-HP	CytoSorb
Characteristic	Nonselective	Nonselective	Nonselective	Semiselective	Selective	Nonselective
Year of development	Flat sheet in 1972, hollow fiber in 1980	Flat sheet in 1998, hollow fiber in 2000	—	2009	1994	2011
Adsorption material	A copolymer of acrylonitrile and sodium methallyl sulfonate	Treated with cationic polymer on the basis of AN69	Polymethyl methacrylate	Polymerized by acrylonitrile and methallyl sulfonate	Polymyxin B bonded to the surface of polystyrene derivative fibers	Divinylbenzene copolymer beads with biocompatible
Cytokines removal	Yes; Up to 35 kDa	Yes; Up to 35 kDa	Yes; Up to 65 kDa	Yes; Up to 35 kDa	No	Yes; Up to 60 kDa
Endotoxin removal	No	No	Yes	Yes	Yes	No
Main application fields	Dialysis, sepsis	Dialysis, sepsis	Dialysis (PMMA-CVVH)	Dialysis, sepsis	Sepsis, pulmonary diseases	Sepsis, septic shock, AKI, COVID-19, ECMO, CPB