STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages

Figure 1

The expression of STING in macrophages was induced in liver IRI.C57/B6 mice were subjected to liver IRI. (a) STING expression in the sham group and the IRI group in the presence or absence of liposomes (20 mM, 200 μl/per mouse) was measured by Western blotting. (b) Relative expression of STING in each group. (c) STING expression in each group was measured by immunohistochemistry (scale bar, 50 μm). (d) The colocalization of F4/80 and STING in KCs was measured by immunofluorescence in each group (scale bar, 100 μm). All data are shown as the ( mice per group). , , and .

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